Mic10 Oligomerization Pinches off Mitochondrial Cristae

摘要

The mitochondrial contact site and cristae organizing system (MICOS) complex is essential for normal mitochondria biogenesis and morphology. In this issue, Bohnert et al. (2015) and Barbot et al. (2015) demonstrate that a MICOS core subunit, Mic10, is crucial for mitochondrial cristae formation by forming oligomers at the cristae junctions.